diff --git a/.github/workflows/build.yml b/.github/workflows/build.yml
index 54d1043e3e..3e5a90e55e 100644
--- a/.github/workflows/build.yml
+++ b/.github/workflows/build.yml
@@ -174,6 +174,8 @@ jobs:
               cfg
               pool
               ramfunc
+
+              peripherals-taken
           )
 
           for ex in ${exs[@]}; do
diff --git a/ci/expected/peripherals-taken.run b/ci/expected/peripherals-taken.run
new file mode 100644
index 0000000000..e69de29bb2
diff --git a/examples/peripherals-taken.rs b/examples/peripherals-taken.rs
new file mode 100644
index 0000000000..cd4ba0f0ed
--- /dev/null
+++ b/examples/peripherals-taken.rs
@@ -0,0 +1,16 @@
+#![deny(unsafe_code)]
+#![deny(warnings)]
+#![no_main]
+#![no_std]
+
+use cortex_m_semihosting::debug;
+use panic_semihosting as _;
+
+#[rtic::app(device = lm3s6965)]
+const APP: () = {
+    #[init]
+    fn main(_: main::Context) {
+        assert!(cortex_m::Peripherals::take().is_none());
+        debug::exit(debug::EXIT_SUCCESS);
+    }
+};
diff --git a/macros/src/codegen/pre_init.rs b/macros/src/codegen/pre_init.rs
index 1f1735d2d3..c6bd61e86a 100644
--- a/macros/src/codegen/pre_init.rs
+++ b/macros/src/codegen/pre_init.rs
@@ -43,6 +43,13 @@ pub fn codegen(
         let mut core: rtic::export::Peripherals = core::mem::transmute(());
     ));
 
+    if app.args.cores == 1 {
+        stmts.push(quote!(
+            // To set the variable in cortex_m so the peripherals cannot be taken multiple times
+            let _ = cortex_m::Peripherals::steal();
+        ));
+    }
+
     let device = extra.device;
     let nvic_prio_bits = quote!(#device::NVIC_PRIO_BITS);